Courses Description
1216217 Pharmaceutical Organic Chemistry-I :: 4 Credit Hours
The course aims to give the pharmacy student the essential knowledge in the chemistry of organic compound and functional groups to help him understand the structure and reactivity of chemical entities mainly those used as pharmaceuticals and drugs and the importance of organic compounds in pharmacy- in relation to drug action and toxicity. The course will concentrate on atomic and molecular structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy- in relation to drug action and toxicity. The chemistry of aliphatic compounds cyclic and alicyclic, saturated and unsaturated alkyl halides, nucleophilic substitution mechanisms, hydroxyl functional group and its reactivity, delocalization and conjugation, elimination and addition reactions, formation and reactions of enols and enolates are to be covered. The course will concentrate at organic reactions and their applications to drug discovery and development. Prerequisite:0304102
1216218 Pharmaceutical Organic Chemistry-II :: 4 Credit Hours
The major topics will include the concept of aromaticity and anti-aromatic structures, reactivity of benzene nucleus-mechanism of aromatic electrophilic substitution, and the effect on reactivity and orientation of ring substituent and their pharmaceutical importance. Acidity of organic molecules, the chemistry of carbonyl group (ketones, aldehydes, carboxylic acid), and its role in biologically active molecules. The chemistry of the amino group and the basicity of organic compounds, followed by the amino acids and peptides chemistry will be addressed. Since heterocyclic systems are key components in drugs and pharmaceuticals, heterocyclic compounds (saturated and unsaturated) carbohydrates, nucleosides, nucleotides and nucleic acids will be dealt with extensively. Organic reactions and their applications to drug discovery and development. Spectral methods (IR, UV-VIS, NMR, and MS) used for analyzing and structural identification of pharmaceuticals and drugs. The course is designed to focus on key elements of organic chemistry with extensive use of pharmaceutical and biochemical illustrations and examples designed to provide a thorough grounding in fundamental chemical principles. Prerequisite:1216217
1216219 Pharmaceutical Organic Chemistry Lab. 1 :: 1 Credit Hour
This laboratory will give the pharmacy students the principles of organic chemistry techniques which include physical tests: melting point, boiling point, solubility, recrystalization, refractive index, surface tension and specific angle of rotation for optically active drugs. Also this course includes the Isolation of drugs from their natural sources, by means of extraction, steam distillation, chromatography...est. In addition to all the above techniques identification of alcohols, synthesis of some alkyl halides and alkenes will be carried out. Prerequisite:0304102
1216220 Pharmaceutical Organic Chemistry Lab. 2 :: 1 Credit Hour
Upon completing this laboratory, pharmacy students will be able to identify drugs by systematic identification through:
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Chemical tests that identify the different functional groups of organic compounds.
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Spectroscopy (FT-IR, UV-VIS, NMR)
Also in this laboratory the students will prepare some popular drugs such as: Aspirin, Wintergreen, Urotropine, Paracetamol, Phenacetin, p-methylacetophenone (sun protector) and Sulfanilamide antibiotics. Prerequisite:1216219
1215221 Physical Pharmacy-1 :: 3 Credit Hours
The course will introduce pharmacy students to principals of physical chemistry and its application in pharmaceutical sciences. The course will help the student in acquiring essential knowledge in order to predict the stability, solubility, compatibility and the biological action of drug products. The broader goal of this course will be an insight into methods to develop new delivery systems and to improve upon the various modes of administration. Topics that will be covered include: An introduction to dimensions and units, some basic elements of mathematics, statistical methods and the analysis of error, precision and accuracy. Basic principles of physical pharmacy: States of matter, binding forces between molecules, gaseous, liquid and solid crystalline states, liquid crystalline states, supercritical fluids, thermal analysis, phase equilibrium and the phase rule determination of physical properties of molecules. Thermodynamics, first, second and third law. Free energy functions and applications. Equilibrium phenomena, nonelectrolytes, solutions of electrolytes, buffered and isotonic solutions, ionic equilibrium, electromotive force and oxidation-reduction, solubility and distribution phenomena. Prerequisite:0304102
1215222 Physical Pharmacy-2 :: 2 Credit Hours
This course is aimed at applying chemical and physical principles into the design of drug delivery systems and understanding the kinetics of drug release and absorption.
Topics will include the kinetic phenomena, diffusion, steady state diffusion, diffusion through membranes, assessing drug diffusion and absorption, biological diffusion, drug release and the Fick's law, methods and apparatus for dissolution testing. Interfacial phenomena, liquid interfaces, application of surface active agents, coarse dispersions and colloids. Rheology, Newtonian systems, thixotropy, determination of rheologic properties. Prerequisite:1215221
1215201 Introduction to Pharmacy and Pharmaceutical Calculations :: 3 Credit Hours
An introduction and overview of the profession of pharmacy., discussion of career opportunities and the skills involved in providing efficient pharmaceutical care. The course introduces the student to some basic medical terminology, abbreviations, reading and interpreting prescriptions, use of standard references as well as performing calculations based on individual patient needs and characteristics as well as computation required for accurate preparation of solid and liquid dosage forms, injectable medications, extemporaneously compounded products, dilutions, percentage preparations, milliequivalents and millimoles, and displacement values. Prerequisite: None
1216215 Pharmaceutical Analytical Chemistry :: 3 Credit Hours
This course deals with the classic analytical methods of analysis that are applied to pharmaceutical compounds covering theory, chemical principals and calculations. In addition, this course familiarizes students with qualitative and quantitative methods of analysis, including different types of titrimetric analysis and their application for analysis of pharmaceutical preparations. Prerequisite:0304102
1216216 Pharmaceutical Analytical Chemistry Lab :: 1 Credit Hour
This course train students on qualitative and quantitative methods of analysis, including different types of titrimetric analysis and their application for analysis f pharmaceuticals. Experiments include neutralization titration of strong and weak acidic and basic drugs, non-aqueous titration, argentometric titration, compleximetric titration, redox titration, iodometric titration and Karl Fisher titration. Prerequisite:0304102
0602215 Physiology 1 :: 4 Credit Hours
A comprehensive course dealing with the various aspects of human physiology with emphasis placed on the maintenance of normal functions. Discussion of cell physiology including nerve and muscle cell function as well as the pulmonary, cardiovascular and gastrointestinal physiology. Prerequisites:0601126& 0604110
0602226 Physiology 2 :: 4 Credit Hours
A continuation of Human Physiology 1. It covers the following Systems: Renal, reproduction, endocrine and neurophysiology, with emphases on control mechanisms, water and electrolyte balance and acid base balance
This class also includes a laboratory that encompasses experiments and demonstrations covering certain aspects of the topics discussed in physiology I and II. Prerequisite:0602215
0605211 Basic Biochemistry :: 3 Credit Hours
This course is designed to provide an understanding of the structure of the chemical components of living matter. The course will cover the four major classes of biological molecules: proteins, carbohydrates, lipids, and nucleic acids.
Emphasis will be on the chemical properties and three-dimensional structure of these molecules in relationship to their biological function. Principles of bioenergetics, the mechanisms of enzyme action, enzyme kinetics, and the control mechanisms which regulate enzymatic reactions will be discussed. Prerequisite:0304102
0605222 Metabolic Biochemistry :: 3 Credit Hours
This course will examine the metabolic pathways and regulatory processes occurring in biological systems and to develop an understanding of some of the sophisticated levels of control within and between metabolic pathways. Prerequisite:0605211
0605223 Biochemistry lab :: 1 Credit Hour
This course Includes 11 laboratory experiments in both basic and metabolic biochemistry. It includes basic skills in the practical work in biochemistry such as basic measurements, weighing, volumetric measurements, pH measurement, Pipetting and dilutions, buffers and buffer preparation and molar solutions preparations. The student will learn the basics of spectrophotometery, measurements in enzyme kinetics, electrophoresis, blood chemistry, carbohydrates, proteins and DNA chemistry. Prerequisite:0605211
0604313 Basic Immunology :: 2 Credit Hours
This course deals with basic principles of immunology and their use to understand the cause of immunological and inflammatory diseases and the basis of immunoprophylaxis and immunotherapy. A brief discussion of the application of genomics to future drug development is included. Prerequisite:0604110
1216301 Natural Products Chemistry :: 3 Credit Hours
This course is dedicated to study the chemistry, biosynthesis and biological function of secondary metabolites of living organisms including Polypeptides, Terpeniods, Phenylpropanoids, Alkaloids, Glycosides, Resins, and other constituents of pharmaceutical and medicinal interests. Prerequisite: Faculty Approval
1216401 Pharmacognosy :: 2 Credit Hours
This course is concerned with the study of drugs from plants. It covers the anatomical structure of plant cells and plant tissue organs, structure development, theory and practice of classification, speciation and environmental variations. Knowledge about the morphological, histological, and other characteristics of the crude drug and its uses is provided. Prerequisite: Faculty Approval
0604311 General Microbiology :: 4 Credit Hours
A general microbiology course to acquaint students with microorganisms and their activities. Microbial cell structure and function, metabolism, microbial genetics, and the role of microorganisms in disease, immunity, and other selected applied areas will be covered.
The practical part covers a variety of microbiological techniques and experiments to illustrate the major concepts covered. Prerequisites:0604110
1215311 Pharmaceutics 1 :: 3 Credit Hours
The application of physical chemical principles in the design, manufacture, and evaluation of different pharmaceutical dosage forms. The course will cover pre-formulation studies, and formulation of liquid and solid dosage forms. Prerequisites:125201 &1215222
1215312 Pharmaceutics 2 :: 3 Credit Hours
A continuation of pharmaceutics I, the application of physical chemical principles in the preparation of powders, colloids, suspensions, emulsions, solids and topical dosage forms and the formulation factors affecting drug availability. Prerequisite:1215311
1215313 Pharmaceutics Lab :: 1 Credit Hour
The laboratory is designed to allow the student to apply pharmaceutical principles and to develop proficiency when compounding selected formulations as syrups, elixirs, lotions, emulsions, creams, ointments, capsules, and suppositories encountered in Community and Hospital Pharmacies. Prerequisite:1215311
0606211 First Aid :: 1 Credit Hour
Basic medical assessment and procedures followed in cases of emergency medical situation and minor injuries. Prerequisites: None
0603314 Basic Pathology :: 5 Credit Hours
This course focuses on the disease processes and mechanisms of tissue injury to organ systems during selected disease states. Emphasis is placed on the specific alterations, derangements and mechanisms, which disrupt normal physiology. Various disorders of the Cardiovascular, Respiratory, Renal, Endocrine and Central Nervous System are presented to provide the students with the rationale for drug therapy. Prerequisite:0602226
0602315 Pharmacology 1 :: 4 Credit Hours
This course deals with fundamental principles of pharmacology such as pharmacokinetics and pharmacodynamics. It discusses physiologic and biochemical mechanisms related to the development of diseases, drug receptor interactions, absorption, distribution, and elimination mechanisms. This information is further on used to study the effects of drugs on the Autonomic Nervous system, Cardiovascular system, Respiratory system, kidney, Blood, and Immune systems. Prerequisites:0605223
0602316 Pharmacology 2 :: 4 Credit Hours
A continuation of pharmacology I, discussion of drugs acting on the Central Nervous system, Chemotherapeutic agents, Endocrine System, and Gastrointestinal agents. Prerequisites:0602315
1216352 Medicinal Chemistry 1 :: 3 Credit Hours
Introduction to the concepts required to understand drugs as organic chemicals whose biological activities are derived from their chemical structures, physicochemical properties, and metabolic pathways. The course continues with a discussion of specific drug classes by covering the chemistry and mechanism of action of drugs affecting the Peripheral and Central Nervous systems. Prerequisite:1216218
1216451 Medicinal Chemistry 2 :: 3 Credit Hours
Continuation of Medicinal chemistry-1. Chemical and Biochemical principles governing the properties of other drug classes including Cardiovascular agents, Diuretics, Hormones, Antiinflammatories, Steroids, Antidiabetics, and Chemotherapeutics. Prerequisite:1216352
1216452 Medicinal chemistry 3 :: 3 Credit Hours
Continuation of Medicinal chemistry-2. Deals primarily with Antibiotics, Antifungals, Antimycotics, and Antivirals. Elements of biotechnology will be introduced. Prerequisites:1216451
1214441 Biopharmaceutics and Pharmacokinetics :: 3 Credit Hours
Study of the time course of drug absorption, distribution, elimination, and drug accumulation. Concepts of Clearance, Half Life, and Volume of Distribution after single and multiple oral and intravenous dosing regimens are covered. Prerequisites: Faculty Approval
1215431 Industrial Pharmacy :: 3 Credit Hours
The technology and processes of manufacturing drug products. Unit operations including drying, mixing, and filtrations. Tableting and tablet coating, capsules and micro encapsulation techniques are presented. Prerequisite:1215312
1215432 Industrial Pharmacy Lab :: 1 Credit Hour
This is the practical part of the Industrial pharmacy course. It includes practical application of unit processes in mixing, granulation, tablet coating, capsule filling, and aspects of quality control. Prerequisites:1215312 &1215313
1215472 Pharmaceutical Technology :: 3 Credit Hours
Recent and more advanced pharmaceutical technology and dosage form are studied during this course including the following: Sustained release technology, therapeutic rate controlled delivery system, micro encapsulation, solubilization technology, cyclodextrin inclusion complexes, nasal drug delivery system pharmaceutical aerosols, ambulatory infusion devices. Prerequisite:1215431
1216461 Pharmaceutical Instrumental Analysis :: 3 Credit Hours
This course includes the principals and applications of the instrumental techniques used for the separation, identification, and determination of pharmaceutical products. The chromatographic methods include HPLC, LC/MS, GC, GC/MS, HS-GC/MS, and CE. Spectroscopic methods include UV visible, fluorescence, FT-IR, NIR, MS, AA, flame emission and ICP. Topics such as extraction of pharmaceuticals, analytical method validation according to FDA, ICH will also be discussed. Prerequisites:1216215 &1216216
1216462 Pharmaceutical Instrumental Analysis Lab :: 1 Credit Hour
This practical course provides the students with the experience of applying the instrumental techniques for the quantitative determination of pharmaceutical products. Selected experiments involve HPLC-PDA, FT-IR, UV visible, polarometry, GC-FID, HS-GC/MS, AA/ICP, and flame photometric analysis. Prerequisite:1216215
1214403 Clinical Chemistry :: 3 Credit Hours
A lecture laboratory course, which examines the clinical diagnostic tests with regard to the chemical, and biochemical rationale of the testing method. Interpretation of the results of the most commonly used laboratory tests and the major factors influencing test values with special emphasis on the effects of medication. Clinical Laboratory data from patients and the use of some of the available kits will be considered. Prerequisites: Faculty Approval
1214571 Pharmacotherapy 1 :: 3 Credit Hours
A course dealing with the clinical applications of drug knowledge to patient care. Disease and drug knowledge will be utilized in the design of therapeutic treatment plans as well as on principles of monitoring drug therapy in patients. This comprises case studies and presentations. Prerequisites:0602316& 1214403
1214572 Pharmacotherapy 2 :: 3 Credit Hours
This course is a continuation of Pharmacotherapy 1. It will utilize the principles introduced in Pharmacotherapy I to various other disease states. Prerequisite:1215471
0605224 Clinical Nutrition :: 2 Credit Hours
This course deals with the foundations of the science of nutrition with emphasis on the nutritional aspects of carbohydrates, lipids, proteins, vitamins, electrolytes and trace elements. Consideration of specific nutritional issues associated with Endocrine, Cardiovascular, Gastrointestinal, Metabolic, Renal and Neoplastic disease states. The role of the pharmacist as a specialist in drug nutrition interactions will be emphasized. Prerequisite:0602316
1214505 OTC Drugs :: 3 Credit Hours
A study of various nonprescription medications, herbs, vitamins, homeopathic products, medical and Para pharmaceutical devices found in pharmacies and used by patients for self treatment and disease monitoring. The rational use and therapeutic efficacy of such medications in common illnesses as cough and cold, dermatological and gastrointestinal disorders, pregnancy and analgesia among others is presented. Prerequisites:0603216&1216452
1214573 Toxicology :: 2 Credit Hours
This course discusses the general principles of toxicology, definitions and types of toxic and poisonous materials. It also deals with the diagnosis, treatment, and management of accidental poisoning from drug over dosage, toxic household products, poisonous plants, venomous animals, industrial and environmental toxicants. Prerequisites:0603216
1217504 Pharmacy Legislation Ethics & Communication :: 2 Credit Hours
Presentation and discussion of the legal principles and laws that affect the practice, of pharmacy in community and institutional settings. Legal concepts covering professionalism, negligence, and liabilities are presented and discussed. This course is also devoted to teach future pharmacists the skills they will need to effectively communicate with, teach and counsel patients about their medications and health. It will provide examples on patient's privacy and professional ethics. Prerequisites:1215201&0602316&1215312
1217502 Pharmacy Management :: 2 Credit Hours
An overview of the principles, practices of administration, operation, and communication applicable to the practice of pharmacy in the community, hospitals, and other health services institutions. Prerequisite: Faculty Approval
1216511 Pharmacopoeial Analysis Laboratory :: 2 Credit Hours
This laboratory focuses on experiments to check the purity profiles and assays of raw materials and quality control of selected pharmaceutical preparations of single or multiple components using procedures as per mentioned in the USP or BP monographs. Emphasis will be given on the procedures involving the use of UV visible, IR, and HPLC and classical titrations for drug analysis and QC of drugs. Prerequisites: 1216461&1216462
1217501 Seminar (Graduation Project) :: 1 Credit Hour
The course will be organized by a faculty member but the whole faculty will participate. Students in their 5th year will be divided into sub-groups and given the opportunity to select a certain topic from a list prepared by each subgroup's adviser. Each student will prepare and deliver a 20-30 minutes presentation that includes title, aims, introduction, recent data available in the literature and conclusions. The presentation will be followed by a discussion (5-10 minutes) that students and faculty members will take part in. The student will submit a written report to his adviser. Prerequisite: Faculty Approval
Faculty Elective Courses
1214581 Clinical Pharmacokinetics :: 3 Credit Hours
Basic pharmacokinetics concepts of drug disposition and response kinetics. The application of these concepts to the clinical setting in monitoring and optimizing specific drug therapies. Emphasis is on learning how to interpret patient specific drug concentration time data. Prerequisite:1214441
1214582 Drug Metabolism and Disposition :: 3 Credit Hours
The biotransformation of drugs and other Xenobiotics is considered. Emphasis is placed on substances that are of therapeutic importance. Consideration of the biochemical mecharisms for these biotransformation, variability, active metabolites and their toxicity, pharmacogenetics, in vitro systems, in vivo methods, and inducers of CYP 450 isozymes are covered. Prerequisite: Faculty Approval
1214583 Drug Discovery and Drug Development :: 3 Credit Hours
A study of the design and discovery of new drugs. Overview of the various traditional and modern approaches and steps that lead to the introduction of new pharmacological agents including the scientific approaches to rational drug design, preclinical evaluations, clinical trials, and regulatory affairs considerations. Prerequisite :0603216
1215584 Perfumes and Cosmetics :: Credit Hours
This course deals with basics of cosmetic preparations, characteristics of the materials used, formulae, their effectiveness, and method of preparation. . Prerequisites :1215431&1215432
1216585 Biological Chemistry :: 3 Credit Hours
The course will cover advanced issues related to biological chemistry including structure, folding, function, reactivity and catalysis of biomolecules (proteins, nucleic acids and carbohydrates). Topics include protein and nucleic acid folding, energetics of macromolecular interactions (kinetics and thermodynamics), and mechanistic enzymology. The folding-function relationship, transition state theory of the enzymatic process will be reviewed as introduction to the directed evolution, RNA aptamers and catalysts. Biophysical methods used in studying biological macromolecular processes such as protein-protein, protein-RNA and DNA-DNA and protein-DNA interaction (X-ray, NMR, flourimetry, calorimetry and mass spectrometry). These issues will addressed in order to understand the structure-folding-conformation and function of macromolecules aiming to design and develop biologically active compounds such specific protein-, DNA- and RNA-binding or cleaving agents. Prerequisite:0605211
1215588 Pharmaceutical Biotechnology :: 3 Credit Hours
This course is designed to acquaint students with the field of biotechnology. Topics will include a history of the biopharmaceutical industry, protein structure, protein production, protein and DNA isolation, analysis and purification, DNA sequencing, SDS-PAGE, southern and western plotting, ELISA, biotechnologically developed drugs, recombinant DNA basics, genetic engineering, monoclonal antibodies, gene delivery (viral and non viral vectors), gene gun, bioreactors, formulation of proteins and peptides, polymeric systems for oral and peptide delivery, vaccines. Prerequisite: Faculty Approval
1214589 Chemotherapeutics of Cancer :: 3 Credit Hours
This course is designed for the pharmacy undergraduate student or medical professional that is interested in the principles of cancer chemotherapy. Initial lectures are focused on the nature of the cancer, describing the genetic, biochemical and pathological changes in cancer cells. Following these introductory sessions the majority of the course is dedicated to reviewing the biochemistry, molecular pharmacology and therapeutic properties of the anticancer and chemotherapeutic agents. These include DNA reactive agents, antimetabolites, intercalators, DNA cutters, alkylating agents, antimitotics, cytoskeletal poisons, cell cycle inhibitors, hormones, molecular targeted agents and biological modifiers. The clinical uses of these therapeutic agents are given together with the basis for their use in combination chemo-therapies. Emphasis is placed on an understanding of the principles of drug action and the molecular mechanisms of each drug. Chemo-preventive agents and examples of ongoing research programs are presented. Prerequisite0602316
1217591 Selected Topic 1: and 1217592 Selected Topic 2 :: 3 Credit Hours
These courses are designed based on the interest of the students and expertise of the faculty members to broaden the knowledge of the students in a selected advanced topic from the field of pharmaceutical sciences. Enrollment requires prior approval by the Faculty. The course numbering (1 or 2) will depend on whether the two courses can be registered in the same semester. Prerequisite: Faculty Approval
1215593 Directed Study :: 3 Credit Hours
This course requires the completion of a research project supervised by one of the faculty members in pharmacy practice, pharmaceutics, medicinal chemistry or pharmacology. A written report and a presentation dealing with the results obtained, is required.
Enrollment requires prior approval of the Instructor. Prerequisite: Faculty Approval
1216595 Drug Design :: 3 Credit Hours
This course focuses on the principles of computational drug design. This course presents an introduction to the applications of drug design and "virtual screening" of bioactive compounds. General topics that will be covered in this course include an overview of the molecular modeling, molecular descriptor, and conformational search of small chemical compounds with major focus on the traditional quantitative structure activity relationships (QSAR). Students will have the opportunity to learn to use several software packages for molecular modeling and drug design. They are expected to complete a semester project that focuses upon the advanced use of the computational resources to the specific problems in drug design. Prerequisite:0602316
1214590 InVivo and In Vitro testing of Drugs :: 3 Credit Hours
This course deals with the evaluation of the biological effects of drugs and other bio-active substances. The student will be enlightened with the in vitro methods for the examination of the effect of drugs and other bio-active chemical on cells and tissues, and also with the in vivo testing in laboratory animals. The course will cover cellular and animal models used in current medical and pharmaceutical research for the development of new drugs. In the laboratory students will apply the methods they learned in the theoretical part on laboratory animals and on extracted tissues and cells. Prerequisite:0603216
1214507 Pharmaceutical Microbiology :: 2 Credit Hours
This course concentrates on medical microbiology and provides core knowledge of infectious disease processes affecting each organ system, as well as working knowledge of the appropriate clinical laboratory investigations. Prerequisite :0604110
